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Distribution-Based Clustering: Using Ecology To Refine the Operational Taxonomic Unit

16S rRNA sequencing, commonly used to survey microbial communities, begins by grouping individual reads into operational taxonomic units (OTUs). There are two major challenges in calling OTUs: identifying bacterial population boundaries and differentiating true diversity from sequencing errors. Curr...

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Detalhes bibliográficos
Main Authors: Preheim, Sarah P., Perrotta, Allison R., Martin-Platero, Antonio M., Gupta, Anika, Alm, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811501/
https://ncbi.nlm.nih.gov/pubmed/23974136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00342-13
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