Pharmacokinetics and Absorption of Paromomycin and Gentamicin from Topical Creams Used To Treat Cutaneous Leishmaniasis

This study evaluated the pharmacokinetics of topical creams containing 15% paromomycin (“paromomycin alone”) and 15% paromomycin plus 0.5% gentamicin (WR 279,396) in patients with cutaneous leishmaniasis. The investigational creams were applied topically to all lesions once daily for 20 days. Plasma...

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Detalhes bibliográficos
Main Authors: Ravis, William R., Llanos-Cuentas, Alejandro, Sosa, Nestor, Kreishman-Deitrick, Mara, Kopydlowski, Karen M., Nielsen, Carl, Smith, Kirsten S., Smith, Philip L., Ransom, Janet H., Lin, Yuh-Jing, Grogl, Max
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811440/
https://ncbi.nlm.nih.gov/pubmed/23877689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00628-13
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