Mutation of RNA Polymerase β-Subunit Gene Promotes Heterogeneous-to-Homogeneous Conversion of β-Lactam Resistance in Methicillin-Resistant Staphylococcus aureus

Three types of phenotypic expression of β-lactam resistance have been reported in methicillin-resistant Staphylococcus aureus (MRSA): heterogeneous, homogeneous, and Eagle-type resistance. Heterogeneous-to-homogeneous conversion of β-lactam resistance is postulated to be caused by a chromosomal muta...

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Bibliographische Detailangaben
Hauptverfasser: Aiba, Yoshifumi, Katayama, Yuki, Hishinuma, Tomomi, Murakami-Kuroda, Hiroko, Cui, Longzhu, Hiramatsu, Keiichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Mechanisms of Resistance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811421/
https://ncbi.nlm.nih.gov/pubmed/23877693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00720-13
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