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Intragenomic Heterogeneity of 16S rRNA Genes Causes Overestimation of Prokaryotic Diversity

Ever since Carl Woese introduced the use of 16S rRNA genes for determining the phylogenetic relationships of prokaryotes, this method has been regarded as the “gold standard” in both microbial phylogeny and ecology studies. However, intragenomic heterogeneity within 16S rRNA genes has been reported...

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Detalhes bibliográficos
Main Authors: Sun, Dong-Lei, Jiang, Xuan, Wu, Qinglong L., Zhou, Ning-Yi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811346/
https://ncbi.nlm.nih.gov/pubmed/23872556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01282-13
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