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Staphylococcus aureus Fatty Acid Auxotrophs Do Not Proliferate in Mice

Inactivation of acetyl-coenzyme A (acetyl-CoA) carboxylase confers resistance to fatty acid synthesis inhibitors in Staphylococcus aureus on media supplemented with fatty acids. The addition of anteiso-fatty acids (1 mM) plus lipoic acid supports normal growth of ΔaccD strains, but supplementation w...

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Détails bibliographiques
Auteurs principaux: Parsons, Joshua B., Frank, Matthew W., Rosch, Jason W., Rock, Charles O.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811263/
https://ncbi.nlm.nih.gov/pubmed/23979734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01038-13
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