Decreased vesicular monoamine transporter 2 (VMAT2) and dopamine transporter (DAT) function in knockout mice affects aging of dopaminergic systems

Dopamine (DA) is accumulated and compartmentalized by the dopamine transporter (DAT; SLC3A6) and the vesicular monoamine transporter 2 (VMAT2; SLC18A2). These transporters work at the plasma and vesicular membranes of dopaminergic neurons, respectively, and thus regulate levels of DA in neuronal com...

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Main Authors: Hall, F. S., Itokawa, K., Schmitt, A., Moessner, R., Sora, I., Lesch, K. P., Uhl, G. R.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811113/
https://ncbi.nlm.nih.gov/pubmed/23978383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.07.031
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