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Engineering multi-stage nanovectors for controlled degradation and tunable release kinetics

Nanovectors hold substantial promise in abating the off-target effects of therapeutics by providing a means to selectively accumulate payloads at the target lesion, resulting in an increase in the therapeutic index. A sophisticated understanding of the factors that govern the degradation and release...

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Detalhes bibliográficos
Main Authors: Martinez, Jonathan O., Chiappini, Ciro, Ziemys, Arturas, Faust, Ari M., Kojic, Milos, Liu, Xuewu, Ferrari, Mauro, Tasciotti, Ennio
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811000/
https://ncbi.nlm.nih.gov/pubmed/23911070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.07.049
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