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R292K Substitution and Drug Susceptibility of Influenza A(H7N9) Viruses

Neuraminidase inhibitors are the only licensed antiviral medications available to treat avian influenza A(H7N9) virus infections in humans. According to a neuraminidase inhibition assay, an R292K substitution reduced antiviral efficacy of inhibitors, especially oseltamivir, and decreased viral fitne...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sleeman, Katrina, Guo, Zhu, Barnes, John, Shaw, Michael, Stevens, James, Gubareva, Larisa V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Centers for Disease Control and Prevention 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810934/
https://ncbi.nlm.nih.gov/pubmed/23965618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3201/eid1909.130724
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