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GIM(3)E: condition-specific models of cellular metabolism developed from metabolomics and expression data

Motivation: Genome-scale metabolic models have been used extensively to investigate alterations in cellular metabolism. The accuracy of these models to represent cellular metabolism in specific conditions has been improved by constraining the model with omics data sources. However, few practical met...

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Detalhes bibliográficos
Main Authors: Schmidt, Brian J., Ebrahim, Ali, Metz, Thomas O., Adkins, Joshua N., Palsson, Bernhard Ø., Hyduke, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810847/
https://ncbi.nlm.nih.gov/pubmed/23975765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt493
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