Genetic Association and Gene-gene interaction of HAS2, HABP1 and HYAL3 Implicate Hyaluronan Metabolic Genes in Glaucomatous Neurodegeneration

Hyaluronan (HA) plays a significant role in maintaining aqueous humor outflow in trabecular meshwork, the primary ocular tissue involved in glaucoma. We examined potential association of the single nucleotide polymorphisms (SNPs) of the HA synthesizing gene – hyaluronan synthase 2 (HAS2), hyaluronan...

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Main Authors: Basu, Kaustuv, Sen, Abhijit, Ray, Kunal, Ghosh, Ilora, Datta, Kasturi, Mukhopadhyay, Arijit
Format: Artigo
Sprog:Inglês
Udgivet: IOS Press 2012
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810698/
https://ncbi.nlm.nih.gov/pubmed/22960332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/DMA-2012-0915
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