IRAK4 and TLR3 Sequence Variants may Alter Breast Cancer Risk among African-American Women

Mounting evidence suggests that imbalances in immune regulation contribute to cell transformation. Women of African descent are an understudied group at high risk for developing aggressive breast cancer (BrCa). Therefore, we examined the role of 16 innate immune single nucleotide polymorphisms (SNPs...

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Autori principali: Yeyeodu, Susan T., Kidd, LaCreis R., Oprea-Ilies, Gabriela M., Burns, Brian G., VanCleave, Tiva T., Shim, Joong-Youn, Kimbro, K. Sean
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2013
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810674/
https://ncbi.nlm.nih.gov/pubmed/24194738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00338
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