A model for prediction of cisplatin induced nephrotoxicity by kidney weight in experimental rats

BACKGROUND: Cisplatin (cis-diamminedichloroplatinum II; CP) is used widely as an antitumor drug in clinics, but is accompanied with renal toxicity. Cisplatin induced nephrotoxicity consists of change in kidney weight, histological changes in kidney and increase in serum creatinine (Cr) and blood ure...

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Main Authors: Nematbakhsh, Mehdi, Ashrafi, Farzaneh, Nasri, Hamid, Talebi, Ardeshir, Pezeshki, Zahra, Eshraghi, Fatemeh, Haghighi, Maryam
Format: Artigo
Jezik:Inglês
Izdano: Medknow Publications & Media Pvt Ltd 2013
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810567/
https://ncbi.nlm.nih.gov/pubmed/24174938
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