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Retrospective analysis of chronomodulated chemotherapy versus conventional chemotherapy with paclitaxel, carboplatin, and 5-fluorouracil in patients with recurrent and/or metastatic head and neck squamous cell carcinoma

BACKGROUND: Chronomodulated chemotherapy has emerged as a new therapy as a result of recent studies focusing on the biological clock. It has been demonstrated that combination chronomodulated chemotherapy of platinum-based drugs and 5-fluorouracil (5-Fu) can significantly improve efficacy and reduce...

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Main Authors: Chen, Dan, Cheng, Jue, Yang, Kai, Ma, Yue, Yang, Fang
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810446/
https://ncbi.nlm.nih.gov/pubmed/24187501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S53098
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