Zeaxanthin Induces Apoptosis in Human Uveal Melanoma Cells through Bcl-2 Family Proteins and Intrinsic Apoptosis Pathway

The cytotoxic effects of zeaxanthin on two human uveal melanoma cell lines (SP6.5 and C918) and related signaling pathways were studied and compared to effects on normal ocular cells (uveal melanocytes, retinal pigment epithelial cells, and scleral fibroblasts). MTT assay revealed that zeaxanthin re...

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Hlavní autoři: Bi, Ming-Chao, Rosen, Richard, Zha, Ren-Yuan, McCormick, Steven A., Song, E., Hu, Dan-Ning
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810440/
https://ncbi.nlm.nih.gov/pubmed/24223611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/205082
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