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Astrocyte enriched miR-29a targets PUMA and reduces neuronal vulnerability to forebrain ischemia

Following transient forebrain ischemia, astrocytes play a key role in determining whether or not neurons in the hippocampal CA1 sector go on to die in a delayed fashion. MicroRNAs (miRNAs) are a novel class of RNAs that control gene expression at the post-transcriptional level and the miR-29 family...

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Autores principales: Ouyang, Yi-Bing, Xu, Lijun, Lu, Yu, Sun, Xiaoyun, Yue, Sibiao, Xiong, Xiao-Xing, Giffard, Rona G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810393/
https://ncbi.nlm.nih.gov/pubmed/24038396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22556
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