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Blocking Toll-like receptor 2 and 4 signaling during a stressor prevents stress-induced priming of neuroinflammatory responses to a subsequent immune challenge

Acute and chronic stressors sensitize or prime the neuroinflammatory response to a subsequent peripheral or central immunologic challenge. However, the neuroimmune process(es) by which stressors prime or sensitize subsequent neuroinflammatory responses remains unclear. Prior evidence suggested that...

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Detalhes bibliográficos
Main Authors: Weber, Michael D., Frank, Matthew G., Sobesky, Julia L., Watkins, Linda R., Maier, Steven F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810175/
https://ncbi.nlm.nih.gov/pubmed/23500798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2013.03.004
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