Utility of OCT3/4, TSPY and β-Catenin as Biological Markers for Gonadoblastoma Formation and Malignant Germ Cell Tumor Development in Dysgenetic Gonads

BACKGROUND: Gonadoblastoma (GB) is regarded as an in situ form of germ cell tumor in dysgenetic gonads, and 30% of patients with GB develop a dysgerminoma/seminoma tumor. OBJECTIVE: Determine whether OCT3/4 and β-catenin are expressed in dysgenetic gonads before GB development and whether TSPY parti...

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Autori principali: Palma, Icela, Garibay, Nayely, Pena-Yolanda, Rocio, Contreras, Alejandra, Raya, Atlantida, Dominguez, Carolina, Romero, Mirna, Aristi, Gerardo, Queipo, Gloria
Natura: Artigo
Lingua:Inglês
Pubblicazione: IOS Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810105/
https://ncbi.nlm.nih.gov/pubmed/23396295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/DMA-130972
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