Structure of a flavivirus envelope glycoprotein in its low-pH-induced membrane fusion conformation

Enveloped viruses enter cells via a membrane fusion reaction driven by conformational changes of specific viral envelope proteins. We report here the structure of the ectodomain of the tick-borne encephalitis virus envelope glycoprotein, E, a prototypical class II fusion protein, in its trimeric low...

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Main Authors: Bressanelli, Stéphane, Stiasny, Karin, Allison, Steven L, Stura, Enrico A, Duquerroy, Stéphane, Lescar, Julien, Heinz, Franz X, Rey, Félix A
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2004
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC380989/
https://ncbi.nlm.nih.gov/pubmed/14963486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600064
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