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Esc4p, a new target of Mec1p (ATR), promotes resumption of DNA synthesis after DNA damage
The DNA damage-responsive protein kinases ATM and ATR phosphorylate SQ/TQ motifs that lie in clusters in most of their in vivo targets. Budding yeast Esc4p contains a cluster of SQ/TQ motifs, suggesting that it might be a target of Mec1p/Tel1p (yeast ATR/ATM). Here it is reported that Esc4p is phosp...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC380984/ https://ncbi.nlm.nih.gov/pubmed/14988729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600129 |
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