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A Low-Molecular-Weight Ferroxidase Is Increased in the CSF of sCJD Cases: CSF Ferroxidase and Transferrin as Diagnostic Biomarkers for sCJD

Aims: Most biomarkers used for the premortem diagnosis of sporadic Creutzfeldt-Jakob disease (CJD) are surrogate in nature, and provide suboptimal sensitivity and specificity. Results: We report that CJD-associated brain iron dyshomeostasis is reflected in the cerebrospinal fluid (CSF), providing di...

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Bibliographische Detailangaben
Hauptverfasser: Haldar, Swati, Beveridge, ’Alim J., Wong, Joseph, Singh, Ajay, Galimberti, Daniela, Borroni, Barbara, Zhu, Xiongwei, Blevins, Janis, Greenlee, Justin, Perry, George, Mukhopadhyay, Chinmay K., Schmotzer, Christine, Singh, Neena
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809602/
https://ncbi.nlm.nih.gov/pubmed/23379482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.5032
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