Liposomes Containing (−)-Gossypol-Enriched Cottonseed Oil Suppress Bcl-2 and Bcl-xL Expression in Breast Cancer Cells

PURPOSE: We have demonstrated that (−)-gossypol-enriched cottonseed oil [(−)-GPCSO] can down-regulate Bcl-2 expression in MCF-7 and primary cultured human breast cancer epithelial cells (PCHBCECs). However, this agent has not been evaluated in vivo due to its limited solubility. We aimed to develop...

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Main Authors: Li, Hong, Piao, Longzhu, Xu, Pingping, Ye, Weiping, Zhong, Saiyi, Lin, Shu-Hong, Kulp, Samuel K., Mao, Yicheng, Cho, Youngah, Lee, L. James, Lee, Robert J., Lin, Young C.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809120/
https://ncbi.nlm.nih.gov/pubmed/21710341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-011-0498-2
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