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H7N9 influenza viruses interact preferentially with α2,3-linked sialic acids and bind weakly to α2,6-linked sialic acids

The recent human outbreak of H7N9 avian influenza A virus has caused worldwide concerns. Receptor binding specificity is critical for viral pathogenicity, and still not thoroughly studied for this emerging virus. Here, we evaluated the receptor specificity of the haemagglutinin (HA) of two human H7N...

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Bibliografiske detaljer
Main Authors: Ramos, Irene, Krammer, Florian, Hai, Rong, Aguilera, Domingo, Bernal-Rubio, Dabeiba, Steel, John, García-Sastre, Adolfo, Fernandez-Sesma, Ana
Format: Artigo
Sprog:Inglês
Udgivet: Society for General Microbiology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809111/
https://ncbi.nlm.nih.gov/pubmed/23950563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.056184-0
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