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Mitochondrial ABC transporters function: the role of ABCB10 (ABC-me) as a novel player in cellular handling of reactive oxygen species

Mitochondria are one of the major sources of reactive oxygen species (ROS) in the cell. When exceeding the capacity of antioxidant mechanisms, ROS production may lead to different pathologies, such as ischemia-reperfusion injury, neurodegeneration, anemia and ageing. As a consequence of the endosymb...

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Detalhes bibliográficos
Main Authors: Liesa, Marc, Qiu, Wei, Shirihai, Orian S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808996/
https://ncbi.nlm.nih.gov/pubmed/22884976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2012.07.013
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