Enhancement of systemic and sputum granulocyte response to inhaled endotoxin in people with the GSTM1 null genotype

OBJECTIVE: To determine if the GSTM1 null genotype is a risk factor for increased inflammatory response to inhaled endotoxin. METHODS: 35 volunteers who had undergone inhalation challenge with a 20 000 endotoxin unit dose of Clinical Center Reference Endotoxin (CCRE) were genotyped for the GSTM1 nul...

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Main Authors: Dillon, Madeline A, Harris, Bradford, Hernandez, Michelle L, Zou, Baiming, Reed, William, Bromberg, Philip A, Devlin, Robert B, Diaz-Sanchez, David, Kleeberger, Steven, Zhou, Haibo, Lay, John C, Alexis, Neil E, Peden, David B
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808962/
https://ncbi.nlm.nih.gov/pubmed/21441173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/oem.2010.061747
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