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A Novel Test for Selection on cis-Regulatory Elements Reveals Positive and Negative Selection Acting on Mammalian Transcriptional Enhancers

Measuring natural selection on genomic elements involved in the cis-regulation of gene expression—such as transcriptional enhancers and promoters—is critical for understanding the evolution of genomes, yet it remains a major challenge. Many studies have attempted to detect positive or negative selec...

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Hlavní autoři: Smith, Justin D., McManus, Kimberly F., Fraser, Hunter B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808868/
https://ncbi.nlm.nih.gov/pubmed/23904330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/mst134
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