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Utilizing Genetic Models of Idiopathic Hypogonadotropic Hypogonadism in Mice and Men to Understand Mechanism of Disease

Mutations in the genes encoding the neuropeptides, kisspeptin and neurokinin B, as well as their receptors, are associated with gonadotropin-releasing hormone (GnRH) deficiency and a failure to initiate and/or progress through puberty. Although the total number of patients studied to date is small,...

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Detalhes bibliográficos
Main Authors: Lippincott, Margaret F., True, Cadence, Seminara, Stephanie B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808847/
https://ncbi.nlm.nih.gov/pubmed/23955308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2013.071910
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