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SERPINB3 is associated with longer survival in transgenic mice

The physiological roles of the protease inhibitor SERPINB3 (SB3) are still largely unknown. The study was addressed to assess the biological effects of this serpin in vivo using a SB3 transgenic mouse model. Two colonies of mice (123 transgenic for SB3 and 148 C57BL/6J controls) have been studied. T...

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Detalhes bibliográficos
Main Authors: Villano, Gianmarco, Ruvoletto, Mariagrazia, Ceolotto, Giulio, Quarta, Santina, Calabrese, Fiorella, Turato, Cristian, Tono, Natascia, Biasiolo, Alessandra, Cattelan, Arianna, Merkel, Carlo, Avogaro, Angelo, Gatta, Angelo, Pontisso, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808827/
https://ncbi.nlm.nih.gov/pubmed/24162160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03056
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