Increased histone H1 phosphorylation and relaxed chromatin structure in Rb-deficient fibroblasts.
Fibroblasts derived from embryos homozygous for a disruption of the retinoblastoma gene (Rb) exhibit a shorter G1 than their wild-type counterparts, apparently due to highly elevated levels of cyclin E protein and deregulated cyclin-dependent kinase 2 (CDK2) activity. Here we demonstrate that the Rb...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
1996
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38088/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8876166/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.21.11510 |
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