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Optogenetic-mediated increases in in vivo spontaneous activity disrupt pool-specific but not dorsal-ventral motoneuron pathfinding

Rhythmic waves of spontaneous electrical activity are widespread in the developing nervous systems of birds and mammals, and although many aspects of neural development are activity-dependent, it has been unclear if rhythmic waves are required for in vivo motor circuit development, including the pro...

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Detalles Bibliográficos
Main Authors: Kastanenka, Ksenia V., Landmesser, Lynn T.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808638/
https://ncbi.nlm.nih.gov/pubmed/24101487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1316457110
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