Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity

Extracellular vesicle (EV)-mediated intercellular transfer of signaling proteins and nucleic acids has recently been implicated in the development of cancer and other pathological conditions; however, the mechanism of EV uptake and how this may be targeted remain as important questions. Here, we pro...

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Detaylı Bibliyografya
Asıl Yazarlar: Christianson, Helena C., Svensson, Katrin J., van Kuppevelt, Toin H., Li, Jin-Ping, Belting, Mattias
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2013
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808637/
https://ncbi.nlm.nih.gov/pubmed/24101524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304266110
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