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Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity
Extracellular vesicle (EV)-mediated intercellular transfer of signaling proteins and nucleic acids has recently been implicated in the development of cancer and other pathological conditions; however, the mechanism of EV uptake and how this may be targeted remain as important questions. Here, we pro...
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Main Authors: | , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
National Academy of Sciences
2013
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3808637/ https://ncbi.nlm.nih.gov/pubmed/24101524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304266110 |
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