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Conditional KIAA1549:BRAF mice reveal brain region- and cell type-specific effects
Low-grade brain tumors (pilocytic astrocytomas)that result from a genomic rearrangement in which the BRAF kinase domain is fused to the amino terminal of the KIAA1549 gene (KIAA1549:BRAF fusion; f-BRAF) commonly arise in the cerebellum of young children. To model this temporal and spatial specificit...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3808469/ https://ncbi.nlm.nih.gov/pubmed/23893969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22415 |
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