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Role of MicroRNA 1207-5P and Its Host Gene, the Long Non-Coding RNA Pvt1, as Mediators of Extracellular Matrix Accumulation in the Kidney: Implications for Diabetic Nephropathy

Diabetic nephropathy is the most common cause of chronic kidney failure and end-stage renal disease in the Western World. One of the major characteristics of this disease is the excessive accumulation of extracellular matrix (ECM) in the kidney glomeruli. While both environmental and genetic determi...

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Detalhes bibliográficos
Main Authors: Alvarez, M. Lucrecia, Khosroheidari, Mahdieh, Eddy, Elena, Kiefer, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808414/
https://ncbi.nlm.nih.gov/pubmed/24204837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077468
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