Ultrastructural Localization of GPR179 and the Impact of Mutant Forms on Retinal Function in CSNB1 Patients and a Mouse Model

PURPOSE. Complete congenital stationary night blindness (CSNB1) is characterized by loss of night vision due to a defect in the retinal ON-bipolar cells (BCs). Mutations in GPR179, encoding the G-protein–coupled receptor 179, have been found in CSNB1 patients. In the mouse, GPR179 is localized to th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Klooster, Jan, van Genderen, Maria M., Yu, Minzhong, Florijn, Ralph J., Riemslag, Frans C. C., Bergen, Arthur A. B., Gregg, Ronald G., Peachey, Neal S., Kamermans, Maarten
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Association for Research in Vision and Ophthalmology 2013
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808102/
https://ncbi.nlm.nih.gov/pubmed/24084093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-12293
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