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Aluminum Hydroxide Influences Not Only the Extent but Also the Fine Specificity and Functional Activity of Antibody Responses to Tick-Borne Encephalitis Virus in Mice

Aluminum hydroxide is the most widely used adjuvant in human vaccines and serves as a potent enhancer of antibody production. Its stimulatory effect strongly depends on the adsorption of the antigen to the adjuvant, which may influence antigen presentation and, as a consequence, the fine specificity...

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Detalhes bibliográficos
Main Authors: Zlatkovic, Juergen, Tsouchnikas, Georgios, Jarmer, Johanna, Koessl, Christian, Stiasny, Karin, Heinz, Franz X.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807910/
https://ncbi.nlm.nih.gov/pubmed/24006434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01690-13
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