TLR3- and MyD88-Dependent Signaling Differentially Influences the Development of West Nile Virus-Specific B Cell Responses in Mice following Immunization with RepliVAX WN, a Single-Cycle Flavivirus Vaccine Candidate

Recognition of conserved pathogen-associated molecular patterns (PAMPs) by host pattern recognition receptors (PRRs) results in the activation of innate signaling pathways that drive the innate immune response and ultimately shape the adaptive immune response. RepliVAX WN, a single-cycle flavivirus...

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Hlavní autoři: Xia, Jingya, Winkelmann, Evandro R., Gorder, Summer R., Mason, Peter W., Milligan, Gregg N.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807881/
https://ncbi.nlm.nih.gov/pubmed/23986602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01469-13
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