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The microbial metabolites, short chain fatty acids, regulate colonic Treg cell homeostasis

Regulatory T cells (Tregs) that express the transcription factor Foxp3 are critical for regulating intestinal inflammation. Candidate microbe approaches have identified bacterial species and strain-specific molecules that can affect intestinal immune responses, including species that modulate Treg r...

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Detalhes bibliográficos
Main Authors: Smith, Patrick M., Howitt, Michael R., Panikov, Nicolai, Michaud, Monia, Gallini, Carey Ann, Bohlooly-Y, Mohammad, Glickman, Jonathan N., Garrett, Wendy S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807819/
https://ncbi.nlm.nih.gov/pubmed/23828891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1241165
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