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Accelerated gene evolution via replication-transcription conflicts

Several mechanisms that increase the rate of mutagenesis across the entire genome have been identified; however, how the rate of evolution might be promoted in individual genes is unclear. A majority of the genes in bacteria are encoded on the leading strand of replication(1–4). This presumably avoi...

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Bibliografski detalji
Glavni autori: Paul, Sandip, Million-Weaver, Samuel, Chattopadhyay, Sujay, Sokurenko, Evgeni, Merrikh, Houra
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807732/
https://ncbi.nlm.nih.gov/pubmed/23538833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11989
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