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Effect of P2X(4) and P2X(7) receptor antagonism on the pressure diuresis relationship in rats

Reduced glomerular filtration, hypertension and renal microvascular injury are hallmarks of chronic kidney disease, which has a global prevalence of ~10%. We have shown previously that the Fischer (F344) rat has lower GFR than the Lewis rat, and is more susceptible to renal injury induced by hyperte...

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Hlavní autoři: Menzies, Robert I., Unwin, Robert J., Dash, Ranjan K., Beard, Daniel A., Cowley Jr., Allen W., Carlson, Brian E., Mullins, John J., Bailey, Matthew A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807716/
https://ncbi.nlm.nih.gov/pubmed/24187541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2013.00305
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