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Calculating statistical power in Mendelian randomization studies

In Mendelian randomization (MR) studies, where genetic variants are used as proxy measures for an exposure trait of interest, obtaining adequate statistical power is frequently a concern due to the small amount of variation in a phenotypic trait that is typically explained by genetic variants. A ran...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Brion, Marie-Jo A, Shakhbazov, Konstantin, Visscher, Peter M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807619/
https://ncbi.nlm.nih.gov/pubmed/24159078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyt179
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