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Increased hypothalamic-pituitary-adrenal drive is associated with decreased appetite and hypoactivation of food motivation neurocircuitry in anorexia nervosa

OBJECTIVE: Corticotropin releasing hormone (CRH)-mediated hypercortisolemia has been demonstrated in anorexia nervosa (anorexia), a psychiatric disorder characterized by food restriction despite low body weight. While CRH is anorexigenic, downstream cortisol stimulates hunger. Using a food-related f...

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Bibliografische gegevens
Hoofdauteurs: Lawson, Elizabeth A., Holsen, Laura M., DeSanti, Rebecca, Santin, McKale, Meenaghan, Erinne, Herzog, David B., Goldstein, Jill M., Klibanski, Anne
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807591/
https://ncbi.nlm.nih.gov/pubmed/23946275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EJE-13-0433
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