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Mapping of the SecA Signal Peptide Binding Site and Dimeric Interface by Using the Substituted Cysteine Accessibility Method

SecA is an ATPase nanomotor critical for bacterial secretory protein translocation. Secretory proteins carry an amino-terminal signal peptide that is recognized and bound by SecA followed by its transfer across the SecYEG translocon. While this process is crucial for the onset of translocation, exac...

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Autors principals: Bhanu, Meera K., Zhao, Ping, Kendall, Debra A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807451/
https://ncbi.nlm.nih.gov/pubmed/23935053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00661-13
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