On the failure of de novo-designed peptides as biocatalysts.
While the elegance and efficiency of enzymatic catalysis have long tempted chemists and biochemists with reductionist leanings to try to mimic the functions of natural enzymes in much smaller peptides, such efforts have only rarely produced catalysts with biologically interesting properties. However...
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| Vydáno v: | Proc Natl Acad Sci U S A |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1996
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38074/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8876152/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.21.11428 |
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