The Homologous Tripartite Viral RNA Polymerase of A/Swine/Korea/CT1204/2009(H1N2) Influenza Virus Synergistically Drives Efficient Replication and Promotes Respiratory Droplet Transmission in Ferrets

We previously reported that influenza A/swine/Korea/1204/2009(H1N2) virus was virulent and transmissible in ferrets in which the respiratory-droplet-transmissible virus (CT-Sw/1204) had acquired simultaneous hemagglutinin (HA(D225G)) and neuraminidase (NA(S315N)) mutations. Incorporating these mutat...

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Autores principales: Pascua, Philippe Noriel Q., Song, Min-Suk, Kwon, Hyeok-Il, Lim, Gyo-Jin, Kim, Eun-Ha, Park, Su-Jin, Lee, Ok-Jun, Kim, Chul-Joong, Webby, Richard J., Webster, Robert G., Choi, Young-Ki
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807396/
https://ncbi.nlm.nih.gov/pubmed/23864624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01333-13
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