Effects of Cellular Activation on Anti-HIV-1 Restriction Factor Expression Profile in Primary Cells

Expression of cell-intrinsic antiviral factors suppresses HIV-1 replication. We hypothesized that cellular activation modulates host restriction and susceptibility to HIV-1 infection. We measured the gene expression of 34 antiviral factors in healthy peripheral blood mononuclear cells (PBMC). Cellul...

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Библиографические подробности
Главные авторы: Raposo, Rui André Saraiva, Abdel-Mohsen, Mohamed, Bilska, Miroslawa, Montefiori, David C., Nixon, Douglas F., Pillai, Satish K.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2013
Предметы:
Virus-Cell Interactions
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807358/
https://ncbi.nlm.nih.gov/pubmed/23966394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02128-13
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