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A Strain-Specific Epitope of Enterovirus 71 Identified by Cryo-Electron Microscopy of the Complex with Fab from Neutralizing Antibody

Enterovirus 71 (EV71) is a picornavirus that causes outbreaks of hand, foot, and mouth disease (HFMD), primarily in the Asia-Pacific area. Unlike coxsackievirus A16, which also causes HFMD, EV71 induces severe neuropathology leading to high fatalities, especially among children under the age of 6 ye...

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Détails bibliographiques
Auteurs principaux: Lee, Hyunwook, Cifuente, Javier O., Ashley, Robert E., Conway, James F., Makhov, Alexander M., Tano, Yoshio, Shimizu, Hiroyuki, Nishimura, Yorihiro, Hafenstein, Susan
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807339/
https://ncbi.nlm.nih.gov/pubmed/23946455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01926-13
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