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Multiple Heparan Sulfate Binding Site Engagements Are Required for the Infectious Entry of Human Papillomavirus Type 16

Human papillomavirus (HPV) entry is accompanied by multiple receptor-induced conformational changes (CCs) affecting both the major and minor capsid proteins, L1 and L2. Interaction of heparan sulfate (HS) with L1 is essential for successful HPV16 entry. Recently, cocrystallization of HPV16 with hepa...

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Détails bibliographiques
Auteurs principaux: Richards, Kathleen F., Bienkowska-Haba, Malgorzata, Dasgupta, Jhimli, Chen, Xiaojiang S., Sapp, Martin
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807331/
https://ncbi.nlm.nih.gov/pubmed/23966387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01721-13
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