Lack of B Cell Dysfunction Is Associated with Functional, gp120-Dominant Antibody Responses in Breast Milk of Simian Immunodeficiency Virus-Infected African Green Monkeys

The design of an effective vaccine to reduce the incidence of mother-to-child transmission (MTCT) of human immunodeficiency virus (HIV) via breastfeeding will require identification of protective immune responses that block postnatal virus acquisition. Natural hosts of simian immunodeficiency virus...

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Hlavní autoři: Amos, Joshua D., Wilks, Andrew B., Fouda, Genevieve G., Smith, Shannon D., Colvin, Lisa, Mahlokozera, Tatenda, Ho, Carrie, Beck, Krista, Overman, R. Glenn, DeMarco, C. Todd, Hodge, Terry L., LaBranche, Celia C., Montefiori, David C., Denny, Thomas N., Liao, Hua-Xin, Tomaras, Georgia D., Moody, M. Anthony, Permar, Sallie R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807290/
https://ncbi.nlm.nih.gov/pubmed/23926338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01887-13
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