Lack of B Cell Dysfunction Is Associated with Functional, gp120-Dominant Antibody Responses in Breast Milk of Simian Immunodeficiency Virus-Infected African Green Monkeys

The design of an effective vaccine to reduce the incidence of mother-to-child transmission (MTCT) of human immunodeficiency virus (HIV) via breastfeeding will require identification of protective immune responses that block postnatal virus acquisition. Natural hosts of simian immunodeficiency virus...

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Main Authors: Amos, Joshua D., Wilks, Andrew B., Fouda, Genevieve G., Smith, Shannon D., Colvin, Lisa, Mahlokozera, Tatenda, Ho, Carrie, Beck, Krista, Overman, R. Glenn, DeMarco, C. Todd, Hodge, Terry L., LaBranche, Celia C., Montefiori, David C., Denny, Thomas N., Liao, Hua-Xin, Tomaras, Georgia D., Moody, M. Anthony, Permar, Sallie R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807290/
https://ncbi.nlm.nih.gov/pubmed/23926338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01887-13
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