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Cellular network entropy as the energy potential in Waddington's differentiation landscape

Differentiation is a key cellular process in normal tissue development that is significantly altered in cancer. Although molecular signatures characterising pluripotency and multipotency exist, there is, as yet, no single quantitative mark of a cellular sample's position in the global different...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Banerji, Christopher R. S., Miranda-Saavedra, Diego, Severini, Simone, Widschwendter, Martin, Enver, Tariq, Zhou, Joseph X., Teschendorff, Andrew E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807110/
https://ncbi.nlm.nih.gov/pubmed/24154593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03039
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