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Caged Naloxone Reveals Opioid Signaling Deactivation Kinetics
The spatiotemporal dynamics of opioid signaling in the brain remain poorly defined. Photoactivatable opioid ligands provide a means to quantitatively measure these dynamics and their underlying mechanisms in brain tissue. Although activation kinetics can be assessed using caged agonists, deactivatio...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The American Society for Pharmacology and Experimental Therapeutics
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3807075/ https://ncbi.nlm.nih.gov/pubmed/23960100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.088096 |
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